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How Diabetes Medications Causes Constipation

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How Diabetes Medications Causes Constipation
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Managing diabetes often involves medications to regulate blood sugar levels. While these drugs are essential for diabetes control, some of them can have an unintended side effect: constipation.  Lets understand that How Diabetes Medications  Causes Constipation.

Types of Diabetes Medications

There are several categories of diabetes medications, and each can affect the body differently:

  1. Insulin: The hormone used to lower high blood sugar levels in type 1 and some type 2 diabetics. It’s typically injected under the skin.
  2. Oral Medications: These include various classes like sulfonylureas, biguanides, and dipeptidyl peptidase-4 (DPP-4) inhibitors, each working through different mechanisms.
  3. GLP-1 Receptor Agonists: These are injectable medications that mimic the actions of incretin hormones to lower blood sugar levels.
  4. SGLT-2 Inhibitors: These drugs prevent glucose reabsorption in the kidneys, leading to increased sugar excretion through urine.

How Diabetes Medications Causes Constipation

While diabetes medications are vital for blood sugar control, some of them can impact the digestive system, leading to constipation. Here’s why:

  1. Slowed Digestion: Certain oral medications, especially opioids, can slow down the digestive tract, resulting in slower bowel movements and constipation.
  2. Altered Gut Hormones: Medications like GLP-1 receptor agonists and SGLT-2 inhibitors can influence gut hormones, which may affect digestion and bowel regularity.
  3. Dehydration: Some medications can increase urination, potentially leading to dehydration, which can contribute to constipation.

Practical Tips for Managing Constipation Caused by Diabetes Medications

Strategies for Relief

Managing constipation while taking diabetes medications requires a proactive approach:

  1. Dietary Adjustments: Incorporate fiber-rich foods like whole grains, fruits, vegetables, and legumes into your diet to promote regular bowel movements.
  2. Hydration: Drink plenty of water to soften stools and prevent dehydration, especially if your medication increases urination.
  3. Regular Exercise: Engage in physical activity to stimulate bowel function and help maintain a healthy weight.
  4. Medication Adjustments: If constipation becomes severe or persistent, consult your healthcare provider about potential medication adjustments or alternatives.

When to Seek Medical Help: Recognizing Warning Signs

While constipation is a common side effect of some diabetes medications, certain signs may indicate the need for medical attention:

  1. Blood in Stools: If you notice blood in your stools or on toilet paper, contact your healthcare provider immediately.
  2. Severe Pain: Intense and persistent abdominal or rectal pain should not be ignored.
  3. Unexplained Weight Loss: Unintended weight loss could indicate underlying issues and should be evaluated.


Constipation caused by diabetes medications is a challenging issue but one that can be managed effectively with the right knowledge and strategies. Understanding why some medications contribute to constipation and taking proactive steps to alleviate it can help you maintain both your digestive health and blood sugar control.

Remember, your healthcare provider is your ally in managing both diabetes and its side effects. If constipation becomes a persistent or severe issue, don’t hesitate to seek their guidance to ensure your overall well-being.

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